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Customized Monoclonal Antibody Service

Phage Display Monoclonal Antibody
  • Wide choices of host animal: mouse/rat/rabbit /llama.
  • Research/therapeutic/IVD /reagent kit, adaptable for all of the applications.
  • Up to 500 clones possible.
  • Library size up to 100-billion.​​​​​​​

Human Naive Antibody Library
  • Pre-built 100-billion-clone human naive antibody library.
  • Full human sequence.​
  • Customized human patient antibody library service.
  • Specially designed for antibody drug discovery.​​

Hybridoma Monoclonal Antibody
  • Mouse/Rat monoclonal antibody.
  • ELISA/FCS/​WB/IHC application guaranteed service.
  • Hybridoma antibody production to gram level.
  • From 1 clone to 200 clones.​​​​

Antibody Engineering and Conjugation​
  • Antibody Sequencing.
  • Antibody affinity maturation /humanization.
  • Bi-specific antibody and antibody fragmentation.
  • BiaCore/ForteBio affinity test.
  • Temperature/pH sensitive antibody.​​

Cell Line Development​ and Industrialization
  • Wide range of host: E.coli, B.Subtilis, Yeast, insect cell, mammalian cell.
  • Large vector bank, unlimited choices.
  • Industry cell line CHO-S, CHO DG44, GS-CHO or IP free cell line available together with industry vectors.
  • ​Expression level boost.​​​​​

Featured Service: Antibody Production
  • Antibody Sequencing and fragmentation. 
  • Industry antibody cell line construction and expression level optimization, up to 4g/L.
  • Up to 200L fermentation volume and purification.
  • ​​Protein characterization: temperature stability, degradation and solubility.​​

Customized Cell Line and Protein Expression Service

Expression, Purification and Pilot Scale
  • From mL to 4000L incubation volume, from μg to g production scale.
  • Special condition: serum free medium, cell-free system.
  • Multiple choices for purification strategy, up to 99.9% purity.
  • GMP certified lab ensuring clinical trial compatibility.
  • CMO production transferable.​​

Protein Engineering and Conjugation
  • Sequence modification, mutation library and fusion protein.
  • Fluorescent/biotin tagging, phosphorylation and PEG conjugation.
  • Protein/peptide drug discovery.
  • 3-D structure analysis and restructure.
  • Special function protein.

Customized Monoclonal Antibody Service

​Human Naive Antibody Library

  • Pre-built 100-billion-clone human naive antibody library.
  • Full human sequence.​
  • Customized human patient antibody library service.
  • Specially designed for antibody drug discovery.​​

Hybridoma Monoclonal Antibody

  • Mouse/Rat monoclonal antibody.
  • ELISA/FCS/​WB/IHC application guaranteed service.
  • Hybridoma antibody production to gram level.
  • From 1 clone to 200 clones.​​​​​​​

Phage Display Monoclonal Antibody

  • Wide choices of host animal: mouse/rat/rabbit /llama.
  • Research/therapeutic/IVD /reagent kit, adaptable for all of the applications.
  • Up to 500 clones possible.
  • Library size up to 100-billion.​​​​​​​

Antibody Engineering and Conjugation​

  • Antibody Sequencing.
  • Antibody affinity maturation /humanization.
  • Bi-specific antibody and antibody fragmentation.
  • BiaCore/ForteBio affinity test.
  • Temperature/pH sensitive antibody.​​

Integrated Solutions for Therapeutic Drug Discovery and Development

Therapeutic drug development is a long process from target analysis, candidate binder generation till CMO production. Due to the high complexity, drug development project requires FbD (Function by Design) minded team with cutting-edge experiment platform and professional project management/operation. Bio Bench was created by a group of talent scientists from top level pharmaceutical companies and CROs who focus on this goal.
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Bio Bench
​a leading antibody and protein CRO company
Bio Bench co. ltd – A one-stop-shop CRO (Contract Research Organization) active in the generation of functional antibody and bio-active protein for drug discovery, IVD kit and biological research. Founded by a group of innovative-spirit-driven biologists in 2013, Bio Bench team has solid know-how and a passion for improving our integrated CRO platform.

20+
Antibodies in preclinical phase
Bio Bench featured research platform:
  • Phage display antibody library.
  • Vivo-Prot™ protein expression and yield optimization.
  • Automated ELISA/HTS/HCS screening.
  • SPR affinity.
  • Bio informatics.
  • In vivo animal model.

10^11
​100-billion-clone Human naive antibody library


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